TRYPANOFORT

COMPOSITION :

Each vial contains:

  • Isometamidium Chloride 250 mg
  • Excipients q.s. to 1 g

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Description

DESCRIPTION

TRYPANOFORT is a highly effective trypanocidal treatment containing Isometamidium Chloride, designed for both curative and prolonged preventive action against a wide range of Trypanosoma species. It is formulated for use in a 2% aqueous solution, ideally prepared fresh at the time of administration.

INDICATIONS:

INDICATIONS TRYPANOFORT is indicated for the treatment and prevention of trypanosomiasis caused by:

  • T. congolense and T. vivax in cattle, sheep, goats, and horses.
  • T. brucei and T. evansi in cattle, buffaloes, camels, horses, and dogs.

KEY BENEFITS

  • Rapid curative action.
  • Prolonged preventive efficacy lasting 2 to 4 months, depending on the disease challenge level.

DOSAGE AND ADMINISTRATION:

  • Prepare a 2% solution by dissolving 250 mg of Isometamidium Chloride in 12.5 mL of sterile water (or boiled and cooled/distilled water when sterile water is not available).
  • Dosage: Administer 0.5-1 mg/kg body weight via intramuscular (IM) Injection, depending on species.

IMPORTANT GUIDELINES

  • Always use sterile syringes and needles.
  • For doses exceeding 15 mL, split the total volume and inject at two different sites to reduce risk of tissue irritation.
  • When using intravenous injection, administer slowly and avoid blood contamination in the syringe.
  • Prepare the solution immediately before use. If necessary, previously prepared solutions may be used if stored in sealed containers at +2°C to +15°C for no longer than 24-48 hours.

RECOMMENDATIONS

  • Ensure the entire dose is injected into the muscle before withdrawing the needle to avoid leakage into subcutaneous tissue.
  • Avoid damaging critical structures (e.g., sciatic nerve, vertebral column) during deep IM injection.
  • Do not repeat treatment within one month of a previous administration.
  • Follow strict aseptic preparation and injection techniques.

PRECAUTIONS

  • Store in a cool, dry place.
  • In the event of accidental human ingestion, induce vomiting and seek immediate medical attention.
  • At slaughter, excise and discard any lesions at the injection site.

WITHDRAWAL PERIODS

  • Meat: 30 days
  • Milk: Nil PRESENTATION
  • Available in 50 per vial